Heartland Assays

3-Methylhistidine (3MH)


Sheffield-Moore M, Dillon EL, Randolph KM, et al. 2013

Isotopic decay of urinary or plasma 3-methylhistidine as a potential biomarker of pathologic skeletal muscle loss. J Cachexia Sarcopenia Muscle. 5(1):19-25, 2013.
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Gaugler M, Brown A, Merrell E, et al. 2011

PKB signaling and atrogene expression in skeletal muscle of aged mice. J Appl.Physiol 111 (1):192-199, 2011.
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Aranibar N, Vassallo JD, Rathmacher J, et al. 2011

Identification of 1- and 3-methylhistidine as biomarkers of skeletal muscle toxicity by nuclear magnetic resonance-based metabolic profiling. Anal.Biochem. 410 (1):84-91, 2011.
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Tamboli RA, Hossain HA, Marks PA, et al. 2010

Body Composition and Energy Metabolism Following Roux-en-Y Gastric Bypass Surgery. Obesity.(Silver.Spring)18(9):1718-1724, 2010.
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Molina PE, McNurlan M, Rathmacher J, et al. 2006

Chronic alcohol accentuates nutritional, metabolic, and immune alterations during asymptomatic simian immunodeficiency virus infection. Alcohol Clin.Exp.Res. 30 (12):2065-2078, 2006.
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Yang H, Pettigrew JE, Johnston LJ, et al. 2000

Effects of dietary lysine intake during lactation on reproductive performance, blood borne metabolites and hormones in primiparous sows. J. Anim. Sci. 78:1001-1009, 2000.
no abstract available

John A. Rathmacher, Ph.D. 2000.

Measurement and Significance of Protein Turnover. In: Farm Animal Metabolism and Nutrition, J. P. F. D'Mello (ed). CAB International, Wallingford.
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Rathmacher JA, and SL Nissen. 1998

Development and application of a compartmental model of 3-methylhistidine metabolism in humans and domestic animals and humans. In: Mathematical Modeling in Experimental Nutrition. A. Clifford and H-G. Müller, Eds., Plenum Press, New York, Adv Exp Med Biol 445:303-24, 1998
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Van dem Hemel-Grooten HNA, Rathmacher JA, Garssen GJ, et al. 1998

Whole body 3-methylhistidine production rate and proteinase activities in different skeletal muscles. Livestock Prod. Sci. 55:145-156, 1998.
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Rathmacher JA, Nissen SL, Paxton RE, Anderson DB, 1996

Estimation of 3-methylhistidine production and muscle mass in swine by compartmental analysis. J. Anim. Sci. 74:46-56, 1996.
no abstract available


Rathmacher JA, Flakoll PJ, Nissen SL, 1995

A compartmental model of 3-methylhistidine metabolism in humans. Am. J. Physiol.269(Endocrinol. Metab. 32):E193-E198, 1995.
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Grooten HNA, Koohmaraie M, Yen JT, 1995

Relationship between proteinase activity and myofibrillar protein degradation in porcine skeletal muscles during protein deficiency. J. Anim. Sci. 73:2272-2281, 1995.
no abstract available


Rathmacher JA, Link GA, Nissen SL, 1993

Measurement of 3-methylhistidine production in lambs by using compartmental-kinetic analysis. Br. J. Nutr. 69:743-755, 1993.
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Rathmacher JA, Link GA, Nissen SL, 1992

Technical Note: The use of a compartmental model to estimate the de novo production rate of Nt-methylhistidine in cattle. J. Anim. Sci. 70:2104-2108, 1992.
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Rathmacher JA, Link GA, Flakoll PJ, Nissen SL, 1992

Gas chromatographic-mass spectrometric analysis of stable isotopes of 3-methylhistidine in biological fluids: application to plasma kinetics in vivo. Biol. Mass Spectrom. 21:560-566, 1992.
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